« June 2006 | Main | August 2006 »

July 30, 2006

Media Watch: Houston Chronicle reporting continues to be the cream of the crop on perinatal mental health topics

In the wake of the Yates retrial, the Houston Chronicle has published a good Q&A with a psychiatrist Stuart Yudofsky, M.D., chairman of the Menninger Department of Psychiatry at Baylor College of Medicine and chairman of psychiatry at The Methodist Hospital.

Yudofsky does an excellent job of characterizing, in lay language everyone can understand, the vast spectrum of mental health issues that can accompany pregnancy and childbirth - ranging from low-level stress and normal "baby blues" to the extremeley rare disorder of postpartum psychosis.

"Psychiatrist Contrasts 'Baby Blues,' Postpartum Psychosis"

July 29, 2006

A reminder of the good that can come from Yates family heartache

Even within professional circles, many are not aware of the vast amount of good that has come from the tragedy experienced by Andrea Yates and her family - particularly in the policy and prevention arenas.

Within two years after Andrea suffered her psychotic break and killed her children at the family home in Houston, the state of Texas passed groundbreaking legislation that has for the past three years served to prevent the suffering of untold numbers of mothers, children, and families. H.B. 341, "The Andrea Yates Bill," requires that all healthcare providers working with pregnant, birthing and postpartum women - including hospitals, birth centers, physicians, and midwives - provide the woman a resource list of the names, addresses, and phone numbers of professional organizations that provide postpartum counseling or related assistance.

In 2006 the Texas legislature did another good thing by significantly strengthening and expanding the provisions of this law: "The Andrea Yates Bill of 2006". It will serve as an excellent model for other states in the years to come, by bringing birth fathers and other family members into the support network, educating parents about Shaken Baby Syndrome and anger and stress control, and generally providing a more comprehensive coverage of the mental health issues that affect huge numbers of new parents and are part of any holistic healthcare delivery system.

In addition, the Greater Houston chapter of the National Mental Health Association (NMHA) has established the Yates Children Memorial Fund for Women's Health, which provides education and information about postpartum illness to women, their families, and healthcare professionals.

The Yates case was also instrumental in the Houston chapter of NMHA's creation of a "Speak Up When You're Down" education campaign on perinatal mental health. The campaign evolved into the Women's Mental Health Initiative of Houston - a model program that can be emulated by communities in any state.

July 28, 2006

For professionals in the field: New online seminar covers research issues for mental health consumers

The Center for Psychiatric Rehabilitation at Boston University is offering a new Professional Development online seminar, "Research Issues for Mental Health Consumers/Survivors."

The basic concepts, terms, and procedures of research are outlined in this seminar, which "will help participants to become aware of the various roles consumers/survivors can play in a research study, and their rights in the research process." This increased awareness "will allow participants to better understand the research studies that consumers/survivors are involved in, as well as the research study results."

Successful participation in this online seminar earns 10 Professional Development Program (PDP) hours, which may be used for continuing education purposes.

For more info, click here. You can also contact Sue McNamara by email: suemac (at) bu (dot) edu.

Penn State research team: Education & treatment prevent infanticide tragedies

Yet another research team pointing out what the data from dozens of studies tells us - that maternal infanticides can and should be prevented by better education, preventive care, social support and early detection of mental illness, particularly during pregnancy and the first year postpartum.

They also address the complicated question of punishment and treatment for mentally ill mothers who harm their children.

"Penn State Researchers Say Education, Treatment Key to Averting Child Homicides"


The guy who couldn't just walk away

A nice Houston Chronicle piece on Yates attorney George Parnham - the fearless guy who has done as much for the future of mental illness advocacy and policy over the past five years as anyone:

"He couldn't walk away"

Cheers for the Houston Chronicle, whose reporters and editors continue to do the primary research necessary to publish complete and responsible reporting on this story. For readers who want something beyond tabloid headlines and easy answers.

More coverage from the Chronicle today:

"Mental Health Advocates Say Verdict Reflects Awareness"

July 27, 2006

Rusty Yates speaks up

Andrea Yates' now ex-husband, who was, for the most part, a silent observer of the retrial, is speaking up, slamming both the media and the prosecution's portrayal of Andrea's illness.

Unlike in the first round, which ended in a mistrial when one of the witnesses for the prosecution was shown to have knowingly given false testimony, Rusty Yates was not called to the stand this time. However, Rusty's account of Andrea's illness is crucial to understanding what went wrong, and when, and how. He has also served as one of Andrea's best, most tireless advocates as she has been shuffled through the mental health and prison systems.

Also see:

"Rusty Yates: Case was Built on Lies"
CNN

Cheers for PSI, local columnists who speak to broader significance of Yates case

Kudos to El Paso, TX Postpartum Support International (PSI) coordinator and attorney Susan Strelitz, along with her colleague Sandy Liu, for such an articulate editorial piece responding to the verdict in the Andrea Yates trial, and to the issue of postpartum psychosis. With so little understanding of this rare but very serious condition, we desperately need intelligent, proactive voices as part of the public and professional dialogue!

"Postpartum Psychosis Merits New Look"
The El Paso Times

Thanks also to the editors of The Record in New Jersey for their thoughful and research-based argument in this op-ed:

"Beyond the Yates Verdict"

And this from Postpartum Support International (PSI):

"PSI. . . is encouraged by the appropriate recognition and characterization of postpartum psychosis as reflected in today's verdict.

"While postpartum psychosis represents a tiny fraction - less than 1% - of postpartum spectrum disorders, our position remains that with appropriate screening and treatment, such tragedies can and will be prevented. Postpartum mood disorders are family illnesses, community illnesses requiring the vigilance of all those involved in a woman's perinatal healthcare team. We must not allow the tragedies which can result from untreated postpartum psychosis to further stigmatize postpartum depressive / anxiety disorders which are not uncommon (up to 20% of postpartum mothers will experience significant mood disruptions) and highly treatable. Rather we must continue to focus on encouraging women, their families and healthcare team to seek treatment at the earliest symptom recognition with the confidence that full recovery is possible when early detection and screening methods are in place."

To read the full text of PSI's response to yesterday's court ruling in Texas, click here.


July 26, 2006

Yates retrial verdict just announced

The verdict is in on the retrial of Andrea Yates, who has been found not guilty by reason of insanity. Yates will be committed to a psychiatric institution in the state of Texas.

Not only does this verdict close a chapter for the Yates family and for the legal and women's mental health advocates who have worked on Andrea's behalf all these years, but it also stands to have an impact as a precedent for such cases in the courts - and possibly even for reform in what many consider an outdated, insufficient legal code.

"Jury: Yates Not Guilty by Reason of Insanity"
The Associated Press (AP)

"Jury Finds Yates Insane, Not Guilty"
The Houston Chronicle

"Yates Found Not Guilty by Reason of Insanity"
The New York Times

USA Today's story suggests, "Yates Verdict May Signal Opinion Shift"

July 24, 2006

Media Watch: Cheers for the AP

This story from the Associated Press (AP) does a good job of clarifying some of the misconceptions surrounding possible outcomes of the Andrea Yates retrial, in which closing arguments begin today in Houston, Texas:

"Yates to become Prisoner, Regardless"

Kudos to the AP reporters who worked on this story, which helps to set the record straight about the punishment options available to juries sentencing mentally ill women who have commited such crimes. This is the only story of its kind to have been published in the U.S. during the Yates retrial.

July 21, 2006

Mothers need our help!

On the same day that the defense rests in the Houston retrial of Andrea Yates, Women's eNews publishes an interesting editorial commentary from a UCLA research scholar:

"Andrea Yates Shows that Mothers Need Our Help"

July 20, 2006

Water gets muddier on prenatal use of antidepressants

It seems the U.S. Food and Drug Administration (FDA) has issued new warnings on the use of antidepressants during pregnancy, citing the contradictory nature of current research in this area:

The FDA does not recommend that pregnant women at risk for depression either take or forego the use of antidepressants, but says the findings "should be considered" in treatment decisions. In the meantime, the agency advises that "women who are pregnant or thinking about becoming pregnant should not stop any antidepressant medication without first consulting their physician."

Basically, the FDA is confirming what we already knew about the safety of antidepressants during pregnancy: We don't know much of anything.

However, their clear statement that women who are using antidepressants prior to becoming pregnant should NOT discontinue them without consulting their health care provider does reinforce an important truth - that untreated depression and anxiety may pose just as much of a risk to a developing fetus - or more - than antidepressant medication. It's all a risk-vs.-benefit analysis, but you don't have to weigh the risks and benefits alone, in a vacuum. The moral of this story: As long as the science remains contradictory, the best you can do is talk with your care provider(s) to make an informed decision based on your circumstances.

For more coverage of this non-story story, check out:

"Depression Drugs Tied to Infants' Lung Disease"
The Associated Press (AP)

"U.S. Warns of New Antidepressant Risks"
Reuters Health

"FDA Takes Action on Antidepressants & Migraine Drugs"
The New York Times

"FDA Issues Advisory on Antidepressant Use During Pregnancy"
WKYT 27 News, Mountain News

July 19, 2006

Daddies & Depression, Postpartum

An interesting editorial recently ran in the health and medical section of a Boston Herald affiliate newspaper, penned by Dr. Murray Feingold, chief of the National Birth Defects Center and a professor of pediatrics at Boston University School of Medicine:

"Do men get postpartum depression?"

July 17, 2006

ACOG's practice guidelines on birth control & depression

The American College of Obstetricians & Gynecologists (ACOG) issued a new "Practice Bulletin" of clinical managmeent guidelines for ob/gyns last month, "Use of Hormonal Contraception in Women with Coexisting Medical Conditions" (number 73).

Here's an excerpt from their current guidelines in answer to the question, "What are the effects of hormonal contraception in women with depressed mood?":

"Data on the use of hormonal contraceptives in women with depression are limited, but generally show no effect. Women with depressive disorders do not appear to experience worsening of symptoms with use of hormonal methods of contraception."

This ACOG recommendation is a "Level B" type, which means it is "based on limited or inconsistent scientific evidence."

The take-home message? 1.) Based on what we know now, from a limited number of small studies, taking hormonal birth control does not worsen depressive symptoms in women. 2.) We need more studies, and bigger studies, to really know if (and to what extent) hormonal contraceptives may affect depression.

July 15, 2006

Funding available for Michigan nonprofits working on PPD

Good news for Michigan nonprofit organizations working on postpartum depression (PPD) education and referrals.

The state's Blue Cross/Blue Shield is accepting applicants for grant funding, with awards ranging from $5,000 to $50,000 to expand new and existing programs. Since 2001, the company has awarded annual grants to spur early detection and treatment of depression among older adults, teens and new mothers. In 2005, 17 ongoing grants were awarded and are expected to help up to 15,000 Michigan residents.

The deadline to apply for a grant is right around the corner - August 4, 2006.

For more about this opportunity, read the full press release here. To submit your grant proposal, click here.

July 14, 2006

Support Partners Program in Seattle next week

Lest my recent blog posts imply that pharmaceutical companies are, hands down, the "bad guys," here's a perfect example of the good work they can do for communities:

Through its "Support Partners" women-and-depression initiative, Eli Lilly is funding an educational program for women and their support partners in Seattle on Thursday, July 20, with guest speakers including actress Linda Dano sharing her personal story and local physician Dr. Sally Edwards speaking about recognizing symptoms of depression, understanding what can trigger the illness, and how to map out a wellness plan and get help.

A similar program is also planned for Houston in the near future. If you want to be alerted of the details, sign up for the free e-newsletter at the Lilly's Support Partners program website.

July 13, 2006

JAMA Scandal Makes More Headlines

More on the latest scandal rocking The Journal of the American Medical Association - this time on a studiy published in early 2006 on antidepressant use during pregnancy:

"JAMA Says it was Misled by Researchers"
Associated Press (AP)

"Medical Journal Says it was Again Misled"
New York Times

"Authors of JAMA Study Did Not Disclose Relationships with Drug Companies"
Medical News Today

July 12, 2006

Blinded Science, Part 2: JAMA Vows to Tighten the Reins

On the heels of yesterday's blog post, wherein a reporter reveals the conflict of interest behind a recently-published study on antidepressant use during pregnancy...

In what surely must be an embarrassing move for a publication whose credibility is on the line, The Journal of the American Medical Association (JAMA) has published a correction on author disclosure, and the editors say they are "tightening the disclosure requirements" for research published in the journal.

Click here to read the details.

July 11, 2006

Blinded Science: the guessing game of antidepressant use during pregnancy

As if pregnancy isn't challenging enough, body and soul...

A study published in the February '06 issue of The Journal of the American Medical Association (JAMA) made a convincing case for the use of antidepressants during pregnancy for women who need them. Hurray! A ray of evidence-based light, after years of uncertainty on the real risk-vs.-benefit of taking antidepressants during pregnancy. Everyone concerned about antepartum mental health and the health of the developing fetus breathed a collective sigh of relief. All of us who've ever made the tough decision to take an antidepressant during pregnancy could sleep a little better at night.

But now this:A story breaks that the research team has compromised integrity in the form of extensive, undisclosed ties to pharmaceutical makers.

The Wall Street Journal reports today:

But the study, and resulting television and newspaper reports of the research, failed to note that most of the 13 authors are paid as consultants or lecturers by the makers of antidepressants. The lead author - Lee S. Cohen, a Harvard Medical School professor and director of the perinatal and reproductive psychiatry research program at Massachusetts General Hospital - is a longtime consultant to three antidepressant makers, a paid speaker for seven of them and has his research work funded by four drug makers. None of his financial ties were reported in the study. In total, the authors failed to disclose more than 60 different financial relationships with drug companies.

To read the full story, click here.

[Sigh.]

Effexor debate just gets stranger & stranger

You'll notice that I've updated and edited my posts on the Effexor debate coinciding with the Andrea Yates retrial in Texas. That's because following the story has begun to feel like falling down the rabbit hole.

First a medical watchdog group and its "expert" executive director, a Texas M.D., go to the press about a rare but very serious side effect of Effexor XR, which was (apparently) quietly added to Wyeth's drug labeling a year ago with no publicity and no special alerts to practicing physicians prescribing it.

Today, another cadre of "experts" charges that Dolan, the watchdog physician, is a Scientologist and has her own agenda regarding mental health care and psychotropic drugs in general. That her professional opinions are not to be trusted. That she's a crackpot capitalizing on the Yates retrial for her own gain.

And guess whose fate is caught in the balance of these warring "experts"? Andrea Yates, who will get life in prison or life in a psychiatric care facility, depending upon the jury's verdict. Not to mention the millions of Americans who take Effexor XR and are now more baffled and worried about drug safety than ever.

For all the bizarre Effexor XR coverage as it unfolds, check links to these news stories:

"Psychiatrists Blast Claims of 'Homicidal' Drug"
Austin American-Statesman, July 11

"Group Criticizes Effexor Maker for Lack of Warning"
Austin American-Statesman, July 10

"Questions Raised on Yates Drug"
Associated Press (AP), July 10

"Group Warns of Drug Yates Took Before Deaths"
Associated Press (AP), Houston Chronicle, July 10

"Drug Warning Too Late for Andrea Yates"
press release from The Medical Accountability Network, July 10

"Antidepressant Used by Yates Questioned"
Associated Press (AP), July 9

"Group Criticizes Effexor Maker"
Associated Press (AP), July 9

What next?

July 09, 2006

Who Knew?: Effexor's Red Flag

UPDATE: SEE SUBSEQUENT BLOG POSTS ON THE EFFEXOR/YATES STORY AS IT UNFOLDS...

Possibly hedding more light on the Andrea Yates case and sending up red flags for patients across the country... the Ft. Worth Star-Telegram (Texas) has published a story on the antidepressant Effexor, a rare but deadly side effect of the drug, and this week's outcry from medical watchdogs at the height of the Yates retrial.

What most people - including doctors prescribing it - don't know is that "homicidal ideation" was added last year as one of the rare side effects on the drug Effexor XR's label and on Wyeth's website.

Dr. Moira Dolan, executive director of The Medical Accountability Network, said she discovered the labeling change only by accident about two weeks ago, when she stumbled across a seven-month-old FDA MedWatch newsletter from November 2005.

Wyeth, the New Jersey-based manufacturer of Effexor, did not send letters to doctors or issue warning labels.

According to the Star-Telegram's reporting, The U.S. Food and Drug Administration defines "rare" as occurring in less than one in 1,000 people. In the U.S. alone, about 19.2 million prescriptions for Effexor were filled last year, but that does not reflect the total number of people who take the drug, because some of those are refills.

The connection to the Yates infanticide? Shortly before drowning her five children, Andrea Yatess' psychiatrist removed from the anti-psychotic drug Haldol (which had been working quite effectively for her, according to Andrea's self-reports and those of her husband, Rusty). What did Andrea's psychiatrist replace the Haldol with? The antidepressant Effexor.

The Star-Telegram quotes Dolan, an Austin, Texas doctor who is not involved in the Yates case: "People need to be warned that this is a possible side effect. Families don't know to be aware of this possible effect. As doctors, we're not going to look through 36 pages of labeling."

Want to let Wyeth know how you feel about this? Mail to:
Wyeth Pharmaceuticals
5 Giralda Farms
Madison, NJ 07940

July 06, 2006

Pediatricians, Here's Your Wake-Up Call: "The research is so convincing, it practically screams..."

Findings from new research have just been published in the journal Pediatrics, giving another evidence-based boost to the argument that pediatricians can and must screen and refer for postpartum depression.

From United Press International (UPI):
A study published in this month's issue of the journal Pediatrics says asking whether a mother has lost interest and pleasure in doing things lately -- and whether she has been feeling down -- can quickly start the process of getting help for the estimated 10 percent of mothers who are depressed. Researchers reported last month that the children of very depressed parents remain about three times as likely as their peers to suffer from depression, anxiety or addiction. A major study this spring found that when mothers' depression abated, their children showed improvement in their own psychiatric symptoms within three months.

The Boston Globe also gave this latest research some good coverage.

Cheers for Dr. Myrna Weissman of Columbia University's psychiatry department, who pioneered much of the research in this area, recognizing that pediatric physicians and nurses are on the front lines with postpartum women and must increase their own awareness of perinatal mood disorders as a vital part of pediatric health care. With these latest research findings, Weissman is more than ever in a position to make strong recommendations to the pediatrics community, telling The Boston Globe, "The research is so convincing, it practically screams for pediatricians to get involved in treating parents' depression."

Among the studies published in July's issue of Pediatrics:

* In a study looking at the "feasibility" of pediatricians routinely screening moms for PPD, in which rural pediatric practices used brief depression screenig of mothers at well-child visits for children of all ages (using a simple two-question patient health questionnaire): Of 1,398 mothers screened, 17% had 1 of the depressive symptoms and 6% (n = 88) scored as being at risk for a major depressive disorder. During discussion, 5.7% of all mothers thought they might be depressed and 4.7% thought they were stressed but not depressed. Pediatric clinicians intervened with 62.4% of mothers who screened positive and 38.2% of mothers with lesser symptoms. Pediatrician actions included discussion of the impact on the child, a follow-up visit or call, and referral to an adult primary care provider, a mental health clinician, or community supports. This research team concludes that "Routine, brief, maternal depression screening conducted during well-child visits is feasible and detects mothers who are willing to discuss depression and stress issues with their pediatrician. The discussion after screening reveals additional mothers who feel depressed among those with lesser symptoms.The additional discussion time was usually brief and resulted in specific pediatrician actions."

* In the study looking at when and how often pediatricians should screen for depressive symnptoms in moms, the research team used the Center for Epidemiologic Studies' Depression Scale with 3,412 mothers at 2, 4, and 30- to 33-month postpartum interviews. Among the findings: "Mothers with depressive symptoms at 2 to 4 months had reduced odds of using car seats, lowering the water heater temperature, and playing with the child at 30 to 33 months. Mothers with concurrent depressive symptoms had reduced odds of using electric outlet covers, using safety latches, talking with the child, limiting television or video watching, following daily routines, and being more nurturing. Mothers with concurrent depressive symptoms had increased odds of using harsh punishment and of slapping the child on the face or spanking with an object." Their findings and recommendations to pediatricians? "The results of our study underscore the importance of clinicians screening for maternal depressive symptoms during the toddler period, as well as the early postpartum period, because these symptoms can appear later independent of earlier screening results. Providing periodic depressive symptom screening of the mothers of young patients has the potential to improve clinician capacity to provide timely and tailored anticipatory guidance about important parenting practices, as well as to make appropriate referrals."

July 04, 2006

New Research Data on Depression, Pregnancy, & Kids

Interesting new research published in the June issue of the American Journal of Psychiatry. Findings suggest that taking SSRI antidepressants during pregnancy does not increase the risk of internalizing behaviors such as depression, anxiety, or withdrawal in young children. Granted, the sample size is small, but it's comforting data - and hopefully will pave the way for more and bigger studies.

Also in the June issue of the same journal, new research that tracked 151 children of depressed parents for 20 years, looking at long-term correlations. Among the authors findings: The risks for anxiety disorders, major depression, and substance dependence were approximately three times as high in the offspring of depressed parents as in the offspring of nondepressed parents. Social impairment was also greater.

July 03, 2006

Cheers: Dr. David Rubinow & UNC Hospitals

Cheers for Dr. David Rubinow and the University of North Carolina Hospitals for creating a new clinic specializing in women's mood disorders, including postpartum depression and severe premenstrual syndrome.

In a bold move, Dr. Rubinow has moved care for such disorders out of the hospital's Ob/Gyn deparment and into the department of psychiatry, noting the tendency toward missing or misdiagnosing such problems by Ob/Gyn care providers.

Here's an excerpt from the Associated Press story about the UNC Hospitals change:

Rubinow and others who treat hormone-linked mood disorders say the conditions remain under-recognized and undertreated, which can lead to potentially devastating effects. That, they said, is despite broader awareness among both patients and physicians.

Some patients and doctors consider menopause a natural process that should not require medical treatment. Such disorders are often trivialized or not recognized as severe, Rubinow said.

"I think it does an enormous disservice to women to say that those who become depressed ... should simply learn to live with it," he said. "It's a barbaric notion to suggest that people should not get treatment. It's unconscionably stupid."