New study disputes previous findings on hormone-PPD link
A new study published in the Journal of Psychiatric Research was NOT able to confirm previous findings, which have suggested a relationship between depressive symptoms at the end of pregnancy and in the first 5 days after birth and the levels of estrogen and progesterone in a woman's body.
The study looked at the relationship between total levels of the hormones estrogen and progesterone (which undergo massive flux during pregnancy and after giving birth), questioning whether the magnitude of change might be associated with the occurence and intensity of perinatal depression. They found no such connection. In this study, the hormone levels did not make women any more likely to experience PPD.
Possible limitation of this study is its small size, with a sample of just 89 women. Larger samples are going to give more authoritative results.
Based on previous studies, the current theory is that sudden, drastic drops in estrogen levels or hypogonadal levels play a part in causing PPD.
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